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KMID : 0613820100200101476
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Journal of Life Science
2010 Volume.20 No. 10 p.1476 ~ p.1482
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The Effects of Exercise Intensity on MDA Concentration and SOD Activity in Rats
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Ko Ki-Jun
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Abstract
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The purpose of the present investigation was to evaluate the effects of swimming training on response of lipid peroxide (MDA) and superoxide dismutase (SOD) enzyme activity of hyperlipidemic rats. Twenty-five male SD rats (6 weeks old) were randomly divided into a control group and 4 swimming groups after hyperlipidemia induction for 4 weeks through a 1% cholesterol diet. Swimming groups were then divided into unloaded swimming group, low-loaded swimming group, moderate-loaded swimming group and high-loaded swimming group by swimming intensity, and made to swim for 6 weeks (6 days/week). The loaded swimming group rats among the swimming groups swam a lead weight equivalent to 0%, 3%, 5% and 7% of body weight attached to the base of the tail. All data were expressed as mean and standard deviation by using an SPSS/PC? program, and to evaluate the differences between groups, data were analyzed by one-way analysis of variance and Duncan multiple range test (α=0.05) was performed to test the significant levels of differences between groups. The conclusions obtained from this study were as follows: 1) all swimming groups had significantly lower levels of MDA than the control group (p＜0.001). Among the swimming groups, the moderate-loaded group had a significantly lower level than the unloaded group, low-loaded group and high-loaded group (p＜0.001). 2) all swimming groups had significantly higher levels of SOD than the control group (p＜0.01). Among swimming groups, the unloaded group, moderate-loaded group and high-loaded group had significantly higher levels than the low-loaded group (p＜0.01).
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KEYWORD
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Swimming exercise intensity, response of lipid peroxide(MDA), superoxide dismutase(SOD)
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